ABOUT MOLECULAR SENSING & BSI TECHNOLOGY

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Molecular Sensing, Inc. (MSI) is commercializing Back-Scattering Interferometry (BSI), the world’s first label-free, conformation-sensitive, free-solution assay technology for biophysical characterization of small molecule interactions with complex drug targets. This includes crude membrane protein preparations and other biochemically intractable target binding assays in native-like, free-solution environments — no tags or tethering.
Conformational change is the hallmark of protein dynamics and is intimately related to protein function. BSI detects binding-induced target conformational change with high specificity and sensitivity. It allows unlabeled binding affinity measurement, target engagement verification and mechanism-of-action elucidation in a single assay platform, vital to informing pharmacology and medicinal chemistry drug discovery efforts.
MSI currently offers Drug Discovery Services to pharmaceutical
companies and will begin shipments of BSI instrumentation in the
second half of 2014.
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KEY APPLICATIONS OF BSI TECHNOLOGY

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