Conformation-Sensitive Assay Detection for Accelerated Drug Discovery Research


Conformation-Sensitive Assay Detection for Accelerated Drug Discovery Research

Slas_OnDemand_ScreenLearn about the superior analytical power of TruBind™ Back Scattering Interferometry (BSI) technology for molecular interaction studies.

TruBind BSI technology offers significant advantages over conventional methods by providing direct binding Kd determinations and confirming target engagement by leveraging label-free, conformation-sensitive detection. Designed to analyze complex and intractable drug targets maintained in native or native-like environments, this technology platform is ideal for studying allosteric kinases and GPCR’s as membrane preps, solubilized proteins, nanodiscs or amphipols, Ion Channels, RTK’s, Allosteric Contractile Proteins, Tau and Alpha Synuclein Fibrils, Transcription Factors, and Transporter Proteins.

Molecular Sensing’s tutorial begins with a brief review of the science and technology fundamentals and then proceeds to a detailed discussion of the direct application of TruBind BSI technology to a variety of challenging targets. Come learn about TruBind Assay Services and the TruBind 100 System to see how BSI technology can accelerate your drug discovery research.

Presented by Scot Weinberger
Director, Co-Founder, Executive Vice President, Molecular Sensing Inc.

Scot has over 20 years of experience in life science instrumentation development before founding Molecular Sensing. Most recently, he founded GenNext Technologies, a company dedicated to advancing education in translational medicine. Scot was Director of Research Proteomics for Ciphergen Biosystems, where he led R&D in mass spectrometry and molecular interaction technology. Earlier in his career he was VP of R&D at Linear Scientific, which he helped sell to Hewlett-Packard and Spectra-Physics and subsequently held key R&D positions at both companies. Scot’s academic training was in cellular biology with a BS degree and post-graduate medical school training from the University of Nevada, Reno. Scot holds 30 different US and international patents in the areas of life science research.

Originally presented as Exhibitor Tutorial at SLAS2015 in February 2015 Washington, DC.


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