Back-Scattering Interferometry (BSI) provides direct binding Kd determinations with label-free, conformation-sensitive detection, delivering significant advantages versus conventional methods for intractable drug targets in complex matrices.
The team of scientists at Molecular Sensing are working with a growing list of challenging targets as listed below. Over time, our researchers will publish summaries of their work on these targets under the title, “BSI at Work.” Please follow the links below to learn more about our progress with particular targets of interest.
GPCR’s (Class A,B, C)
Ion channels
Receptor tyrosine kinases
Photoredox complexes
Kinases
Protein-protein interactors
Transcription factors
Contractile protein complexes
Protein fibrils
Crude membrane fractions
Lysates & tissue extracts
Nanodiscs, lipoparticles
Serum
